|
Pain syndromes are
a part of many people's daily lives. It can render them disabled
in some manner or it can be a degenerative chronic residual
from trauma or disease processes. The objective was to analyze
the effectiveness of Collagen Type II versus placebo treatment
on these people, and report the results and measure the response
by the subject.
AUTHORS - Drs.
K. Buckman, J. Gutierrez; et al
OBJECTIVE -
To compare the effects of placebo versus Collagen Type II on
the course of pain syndromes.
Placebo - Made
of capsules containing standard ingredients of no nutritional
or synthetic value. Collagen Type II - Each treatment
of 4 capsules containing 2000 mg. of chicken sternal cartilage.
Collagen Type II naturally contains 15% of Glucosamine Sulfate
and 15% of Chondroitin Sulfate.
RESEARCH DESIGN
AND METHODS - We entered 89 random subjects with various
types of pain syndromes. All subjects were interviewed and asked
to describe their subjective pain and where their pain was located.
They were also asked if they had been given a new prescription
or any changes on their current medical regiment. If there were
changes in the subjects regiment, that subject was not included
in the study. Each subject was told the program would last three
months.
The subjects were
asked to follow the directions on the bottle:
1. Take 4 capsules
of the Collagen Type II in the morning with orange juice
2. Take twenty to thirty minutes before they ate breakfast
3. Record what day they responded to treatment
The following descriptions
of pain were given by the subjects:
Rheumatoid Arthritic
Pain
Osteoarthritis Joint Pain
Post Surgical Joint Pain
Post Traumatic Pain
Fibrositis
Gouty Arthritis
Lumbosacral Pain with/without radicular pain
Cervical Spine Pain with/without radicular pain
RESULTS - 89.9%
of the subjects received pain relief at some level within 45
days of taking the Collagen Type II capsules.
Compliance
- All subjects were compliant with taking four capsules a day.
After end trial interviews we found that 9% of the subjects
took more than four, but less than seven capsules a day.
Table 1. Results
of response to pain relief by (X) days:
| DAYS
TO RESPONSE |
0-7
Days |
8-21
Days |
21-45
Days |
Totals |
| Rheumatory Arthritis |
9 |
6 |
3 |
18 |
| Osteoarthritis |
7 |
12 |
5 |
24 |
| Fibrosis |
4 |
7 |
2 |
13 |
| Lumbosacral
w/ history of herniated disc |
3 |
6 |
3 |
12 |
| Chronic Post
Traumatic Pain |
2 |
4 |
3 |
9 |
| Gouty Arthritis |
2 |
|
|
2 |
| Cervical Spine
w/ history of herniated disc |
|
1 |
1 |
2 |
| Placebo |
|
|
(1) |
(1) |
| Non responsive |
|
|
9 |
9 |
| Total |
27 |
36 |
26 |
89 |
The total without a
response of less pain in 45 days was nine or approximately 10.1%
and only (one) placebo subject recorded a response in 45 days.
Side Effects
- Only one subject had nausea. It was noted that he was on other
medications as well.
CONCLUSION
- Collagen Type II treatment had a significant effect on subjective
pain syndromes. Most subjects responded
to Collagen Type II in the first 21 days of the trial.
Many of these pained subjects had previously been on long term,
pharmaceutical treatment programs.
Many subjects responded
by initiating life style changes due to lack of pain. Many were
excited by the increase in their daily activity. The results have
prompted the authors to develop specific disease/pain syndrome
trials in the near future.
ABSTRACT:
Objective - A prospective double blind clinical trial to
compare placebo versus Collagen Type II for subjective pain treatment
over a three month time period.
Research Design and
Methods - We entered 89 random subjects of varying ages and
subjective complaints of pain. This was a crossover double blind
using numbered bottles for the study. Each subject received both
a placebo and Collagen Type II, at a dose of 2 grams/day.
Results - 89.9%
of the subjects responded to reduction of pain.
Conclusions-
Collagen Type ll had a beneficial effect on the cause of various
pain syndromes. |
