UNIQUE FACTS ABOUT
UNIQUE E

UNIQUE E FACT:
 
  Each capsule of UNIQUE E contains a minimum
of 300 mg of d-gamma tocopherol.

About Gamma Tocopherol

Gamma Tocopherol is part of the vitamin E family and has both antioxidant and non-antioxidant functions in the human body. Recent research suggests that:

Gamma Tocopherol inhibits the proliferation of prostate and lung cancer cells and even causes cell death in prostate cancer cells. There were no negative affects on normal prostate cells.*
Gamma Tocopherol is an antioxidant and acts as a potent anti-inflammatory both in vitro and in vivo.**
Gamma Tocopherol has an anti-carcinogenic effect via it's upregulation of PPARgamma activity.***
Taking a vitamin E supplement with only alpha tocopherol instead of the entire tocopherol family depletes the level of gamma tocopherol in the body.****

Unlike other vitamin E supplements that provide little to no gamma tocopherol, UNIQUE E provides a
powerful 300 mg of gamma tocopherol in every capsule. While researchers and marketers alike have only recently recognized the importance of gamma tocopherol, our customers know that A.C. Grace Company has proclaimed the importance of gamma tocopherol for many years. Vitamin E is a complex of molecules that work together synergistically. UNIQUE E is a specialized proprietary formula of concentrated tocopherols specifically designed to provide the highest biological activity and maximum synergistic benefits of the all-natural complex.

References:
* Jiang Q. Wong J, Fyrst H, Saba JD, Ames BN. gamma-Tocopherol or combinations of vitamin E forms induce cell death in human prostate cancer cells by interrupting sphingolipid synthesis. - Jiang Q, Wong J, Ames BN. {gamma} -Tocopherol Induces Apoptosis in Androgen-Responsive LNCaP Prostate Cancer Cells via Caspase-Dependent and Independent Mechanisms.

** Jiang Q, Ames BN. Gamma-tocopherol but not alpha-tocopherol, decreases proinflammatory eicosanoids and inflammation damage in rats. - Jiang Q, Elson-Schwab I, Courtemanche C, Ames BN. gamma-tocopherol and its major metabolite, in contrast to alpha-tocopherol, inhibit cyclooxygenase activity in macrophages and epithe-lial. cells.

*** Campbell SE, Stone WL, Whaley SG, Qui M, Krishnan K. Gamma (gamma) tocopherol upregulates perox-isome proliferator activated receptor (PPAR) gamma (gamma) expression in SW 480 human colon cancer cell lines.

*** Handelman GJ, Machlin LJ, Fitch K, Weiter JJ, Dratz EA. Oral alpha-tocopherol supplements decrease plasma gamma-tocopherol levels in humans. J Nutr. 1985 Jun;115(6):807-13.